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Statistical Reports

Ch 3: Estimated Future Cancer Prevalence [2022]

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Ontario Cancer Statistics 2022 Ch 3: Estimated Future Cancer Prevalence

Cancer prevalence is a measure of the number of people diagnosed with cancer who are alive. This chapter presents projected statistics on the prevalence of cancer in Ontario up to 2034. The projected statistics do not account for the effects of the COVID-19 pandemic.

What's on this page

Prevalent cancer cases include people who were recently diagnosed with cancer and are still under treatment, as well as people who are survivors of the disease. Survivors – defined in this report as people who are 2 or more years past their cancer diagnosis – make up the majority of prevalent cases in these statistics.

Cancer prevalence in Ontario has been rising due to a combination of improved cancer survival, lower mortality from the disease and increasing cancer incidence. Cancer incidence has risen as a result of improved early cancer detection and demographic changes in Ontario’s population, such as increasing life expectancy, and the growth and aging of the population.

Factors Affecting Future Prevalence

Demographic changes

In 2018, about half of all prevalent cancers were among people ages 60 to 79 (see Chapter 7: Cancer Prevalence). The advancing age of the baby boomer generation – people born from 1946 to 1964 and who make up the majority of the 60 to 79 age group – is expected to contribute to the growing incidence of cancer in Ontario. People age 65 and older will represent a larger proportion of cancer cases by 2034 compared with 2018. The greater proportion of seniors and population growth in the coming years are consistent with Ontario’s population projections.[1]

Note: Current and projected incidence counts are based on the National Cancer lnstitute’s Surveillance, Epidemiology and End Results standards for counting multiple primary cancers, which were adopted by the Ontario Cancer Registry for cases diagnosed from 2010 onward.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Figure 3.1 Current and projected incidence counts by sex and age group for all cancers combined, Ontario, 2018 and 2034 (projected)
Age group Males (2018) Females (2018) Males (2034) Females (2034)
00-04 years 84 60 96 74
05-09 years 64 48 61 41
10-14 years 68 49 64 49
15-19 years 118 105 123 90
20-24 years 231 210 214 195
25-29 years 296 350 285 338
30-34 years 388 697 406 643
35-39 years 482 1050 561 1130
40-44 years 651 1476 817 1763
45-49 years 1159 2200 1280 2564
50-54 years 2316 3216 2227 3333
55-59 years 3877 4367 3807 4280
60-64 years 5678 5062 6245 5488
65-69 years 6919 5608 10110 7306
70-74 years 6966 5614 10988 7660
75-79 years 5508 4372 9699 7005
80-84 years 4088 3614 7570 5959
85+ years 3738 4088 6565 6289

Note: Current and projected incidence counts are based on the National Cancer lnstitute’s Surveillance, Epidemiology and End Results standards for counting multiple primary cancers, which were adopted by the Ontario Cancer Registry for cases diagnosed from 2010 onward.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Improving cancer survival

Because cancer survival has improved over time for most cancers (see Chapter 6: Cancer Survival), the risk of cancer survivors developing a late effect of treatment or a subsequent cancer has grown. The proportion of subsequent primary cancers has steadily increased, with about 20% of new cancer cases in 2018 representing a second or subsequent new cancer diagnosis (Figure 3.2). Because multiple cancer diagnoses can have a compounding impact on quality of life [2], knowing the increasing proportion of subsequent cancers can inform the needs around care for future cancer survivors.

Notes:

  1. Number of new cases is based on the National Cancer Institute’s Surveillance, Epidemiology and End Results standards for counting multiple primary cancers, which were adopted by the Ontario Cancer Registry for cases diagnosed from 2010 onward.
  2. First or only primary cancers are cases diagnosed in people with no previous cancer diagnoses, second primary cancers are cases diagnosed in people who had 1 previous cancer diagnosis, and third or later primary cancers are cases diagnosed in people with 2 or more previous cancer diagnoses.
  3. In 2010, 81.7% of new cancer cases were first or only primary cancers, 16.1% were second primary cancers and 2.1% were third or later primary cancers; in 2018, 79.6% of new cancer cases were first or only primary cancers, 17.0% were second primary cancers and 3.4% were third or later primary cancers

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Figure 3.2 Distribution of multiple primary cancers, Ontario, 2010 to 2018
Year of Diagnosis Third or later primary cancers Second primary cancers first or only primary cancers
2010 1570 11818 59857
2011 1940 12746 60983
2012 2139 12707 60405
2013 2216 12950 60881
2014 2356 12931 61653
2015 2683 13609 63130
2016 2664 13378 64560
2017 3068 14676 66793
2018 2908 14410 67503

Notes:

  1. Number of new cases is based on the National Cancer Institute’s Surveillance, Epidemiology and End Results standards for counting multiple primary cancers, which were adopted by the Ontario Cancer Registry for cases diagnosed from 2010 onward.
  2. First or only primary cancers are cases diagnosed in people with no previous cancer diagnoses, second primary cancers are cases diagnosed in people who had 1 previous cancer diagnosis, and third or later primary cancers are cases diagnosed in people with 2 or more previous cancer diagnoses.
  3. In 2010, 81.7% of new cancer cases were first or only primary cancers, 16.1% were second primary cancers and 2.1% were third or later primary cancers; in 2018, 79.6% of new cancer cases were first or only primary cancers, 17.0% were second primary cancers and 3.4% were third or later primary cancers

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Prevalence projections for planning healthcare and social service

While statistics on recent cancer prevalence can be useful for understanding how many people with cancer are currently in different phases of cancer care (see Chapter 7: Cancer Prevalence), estimating the future prevalence of cancer can help health system planners, policy-makers and healthcare service providers anticipate the amount and type of health system resources needed to treat people recently diagnosed with cancer and provide follow-up services to cancer survivors. For example, prevalence projections can help ensure there is adequate distribution of health and social services to meet the future needs of survivors.[3]

In addition to helping predict future resources for treatment and recovery, other jurisdictions have shown that prevalence projections can be analyzed with other data and used by governments to plan for the costs associated with care and other services. Due to the growing cancer prevalence in the United States, cancer care costs were projected to increase 27% from 2010 to 2020.[4] Costs for care will depend on the proportion of people in different phases of survivorship and is expected to be highest in people recently diagnosed with cancer. However, the number of survivors who were diagnosed less than 5 years ago was projected to increase less than the number of cancer survivors who were diagnosed 5 or more years ago. Survivors who were diagnosed 5 or more years ago require supports that fall outside the cancer system and the costs associated with their care can be difficult to determine.[5] Finally, prevalence projections can influence research on the issues that survivors face, such as effects on quality of life, financial hardship and other social challenges.[6]

This chapter presents complete prevalence projections from 2019 to 2034 for all cancers combined and for the current 10 most prevalent cancers in Ontario. “Complete” cancer prevalence describes the number of people alive on a certain date (e.g., at the start of a calendar year) who were ever diagnosed with cancer. Complete prevalence therefore represents a heterogeneous group made up of people who were diagnosed many years ago (and are who likely to be cured of their cancer) and people who were diagnosed only recently (and who may still be undergoing cancer treatment).

Due to differences in methodology, statistics in this chapter and Chapter 7: Cancer Prevalence are not comparable.

Projected Trend in Prevalence

The prevalence of cancer is projected to increase from 2019 to 2034, from an estimated 845,188 people in 2019 to 1,265,216 in 2034 (Figure 3.3). Over this period, the prevalence proportion will have increased from 5,266.8 per 100,000 in 2018 to 5,612.5 per 100,000 in 2034. As in 2019, there is expected to be considerable heterogeneity in the prevalent cancer population in 2034 in terms of cancer type and how long people have survived beyond their cancer diagnosis.

Notes:

  1. Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
  2. Prevalence proportions are per 100,000 and standardized to the age distribution of the 2011 Canadian Standard population.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Figure 3.3 Projected prevalence counts and age-standardized prevalence proportions for all cancers combined, Ontario, 2019 to 2034
Year Prevalent proportion Prevalence proportion
2019 845188 5266.8
2020 875204 5324.4
2021 904984 5387
2022 934775 5416
2023 964697 5448.1
2024 994733 5478.9
2025 1024686 5505.5
2026 1054234 5528.3
2027 1083480 5548.2
2028 1112265 5569.2
2029 1140293 5584.5
2030 1167567 5592.6
2031 1193961 5599.1
2032 1219209 5610.4
2033 1242928 5615.4
2034 1265216 5612.5

Notes:

  1. Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
  2. Prevalence proportions are per 100,000 and standardized to the age distribution of the 2011 Canadian Standard population.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

The number of prevalent cases among males is expected to increase 45%, from 386,404 in 2019 to 558,836 by 2034. In females, the number of prevalent cases is expected to grow 54%, from 458,784 in 2019 to 706,380 in 2034 (Figure 3.4).

While the projected prevalence proportion is expected to continue to increase in females, the projected rate will decrease in males. The increasing prevalence proportion in females will be driven largely by a few cancer types (see next section, Projected prevalence by cancer type).

Notes:

  1. Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
  2. Prevalence proportions are per 100,000 and standardized to the age distribution of the 2011 Canadian Standard population.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Figure 3.4 Projected prevalence counts and age-standardized prevalence proportions by sex for all cancers combined, Ontario, 2019 to 2034
Year Prevalent cases - males Prevalence proportions- males Prevalent cases - females Prevalence proportions - females
2019 386404 5154.1 458784 5462
2020 399730 5191.8 475474 5536.6
2021 412818 5232.4 492166 5617.4
2022 425783 5233.7 508992 5669.2
2023 438657 5237.3 526040 5724.6
2024 451473 5240.8 543260 5777.8
2025 464156 5240.4 560530 5826.7
2026 476532 5235.1 577702 5872.6
2027 488612 5225 594868 5917
2028 500356 5216.2 611909 5962.7
2029 511663 5202.8 628630 6002.3
2030 522508 5182.4 645059 6034.8
2031 532812 5160.1 661149 6065.8
2032 542379 5141.5 676830 6102.5
2033 551015 5115.9 691913 6133.9
2034 558836 5082.6 706380 6157.8

Notes:

  1. Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
  2. Prevalence proportions are per 100,000 and standardized to the age distribution of the 2011 Canadian Standard population.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Projected Prevalence by Cancer Type

Table 3.1 shows that the change in prevalence over time is projected to differ by cancer type. In males and females combined, the prevalence proportion are expected to stay the same between 2019 and 2034. However, large relative increases in the prevalence proportion are expected for thyroid and kidney cancers. In males, the largest relative increases are similarly expected for thyroid and kidney cancers, while in females the greatest increases are expected for uterus and thyroid cancers.

The relative increase from 2019 to 2034 in the prevalence proportion of lung cancer is expected to be higher in females than in males.

Table 3.1 Projected prevalence counts and age-standardized prevalence proportions by cancer type and sex, Ontario, 2019 and 2034
Cancer type Both sexes
Prevalence count (2019)
Both sexes
Prevalence count (2034)
Both sexes
Prevalence proportion (2019)
Both sexes
Prevalence proportion (2034)
Males
Prevalence count (2019)
Males
Prevalence count (2034)
Males
Prevalence proportion (2019)
Males
Prevalence proportion (2034)
Females
Prevalence count (2019)
Females
Prevalence count (2034)
Females
Prevalence proportion (2019)
Females
Prevalence proportion (2034)
All cancers 845,188 1,265,216 5,266.8 5,612.5 386,404 558,836 5,154.1 5,082.6 458,784 706,380 5,462.0 6,157.8
Breast (female) n/a n/a n/a n/a n/a n/a n/a n/a 164,674 236,420 1,937.8 2,013.4
Colorectal 77,097 115,460 470.6 503.6 42,225 64,386 564.6 599.3 34,872 51,074 394.0 421.6
Kidney 25,453 46,693 159.0 212.5 15550 30,531 206.9 296.5 9903 16,162 117.1 137.7
Leukemia 26,695 39,975 170.5 186.1 15,292 23,088 206.3 225.5 11,403 16,887 139.5 151.1
Lung 35,003 49,303 210.4 192.8 15,267 18,538 202.1 158.1 19,736 30,765 220.5 223.3
Melanoma 47,935 71,513 303.9 320.1 23,204 35,617 312.0 330.1 24,731 35,896 302.0 315.9
Non-Hodgkin lymphoma 41,901 67,949 262.9 301.4 22,686 36,772 304.8 349.1 19,215 31,177 226.4 259.3
Prostate n/a n/a n/a n/a 119,093 190,241 1,560.1 1,579.8 n/a n/a n/a n/a
Thyroid 50,917 118,172 342.2 623.8 10,754 26,747 148.0 289.5 40,163 91,425 526.6 937.2
Uterus n/a n/a n/a n/a n/a n/a n/a n/a 33,822 60,849 389.4 516.6

Abbreviation: n/a means not applicable.

Notes:

  1. Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
  2. Prevalence proportions are per 100,000 and standardized to the age distribution of the 2011 Canadian Standard population.

Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Projected Prevalence by Age

The anticipated growth in prevalent cases will vary by age group, with the relative proportion of cases increasing most for people age 60 and older (Figure 3.5).

Ages 0 to 39:

  • In 2019, this age group represented about 4% of prevalent cases. In 2034, they will represent 3% of cases.
  • The number of prevalent cases will increase slightly in this age group, with cases increasing 8%, from 37,222 in 2019 to 40,227 in 2034.

Ages 40 to 59:

  • In 2019, this age group represented 21% of prevalent cases. In 2034, they will represent about 15% of cases.
  • Similar to the youngest age group, a modest increase of 5% will occur among people ages 40 to 59 from 176,393 prevalent cases in 2019 to 185,269 prevalent cases in 2034.

Ages 60 to 79:

  • In 2019, this age group represented about 55% of prevalent cases. In 2034, they will represent 56% of cases.
  • Unlike younger ages, the proportion of prevalent cases will increase substantially in this age group, with cases increasing 52%, from 463,854 in 2019 to 705,601 in 2034.

Ages 80 and older:

  • In 2019, this age group represented about 20% of prevalent cases. In 2034, they will represent 26% of cases.
  • The change in the number of prevalent cases will be highest for people age 80 and older, with prevalent cases nearly doubling from 167,719 cases in 2019 to 334,119 cases in 2034.

Note: Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Figure 3.5 Projected prevalence counts by age group for all cancers combined, Ontario, 2019 to 2034
Year 80 years and older Ages 60 to 79 Ages 40 to 59 Ages 0 to 39
2019 167719 463854 176393 37222
2020 174214 485805 177458 37727
2021 180640 508276 177892 38176
2022 187615 530644 177933 38583
2023 195740 552523 177484 38950
2024 204880 574068 176528 39257
2025 214251 595338 175576 39521
2026 224220 615041 175233 39740
2027 237789 629919 175813 39959
2028 253700 641474 176897 40194
2029 268359 653545 178006 40383
2030 282135 665920 179048 40464
2031 295579 677906 180027 40449
2032 308617 688876 181297 40419
2033 321278 698181 183118 40351
2034 334119 705601 185269 40227

Note: Prevalence counts are based on incidence counts using International Agency for Research on Cancer/International Association of Cancer Registries rules for counting multiple primaries.
Analysis by: Surveillance, Ontario Health (Cancer Care Ontario)
Data source: Ontario Cancer Registry (March 2021), Ontario Health (Cancer Care Ontario)

Interpreting Prevalence Projections with Caution

Prevalence projections can be challenging to derive and interpret because they are a function of 2 other types of data: cancer incidence and survival. Therefore, the projections are sensitive to assumptions made about trends in incidence and trends in survival. For example, although historical incidence data are used to derive future incidence for calculating future prevalence, those data do not account for possible changes in recent practices that could affect the incidence of cancer such as early detection or cancer screening.

The prevalence projections also depend on the accuracy of the forecasts about population size. The approach used in this chapter assumes dynamic projections of the population.

Finally, several statistical methods exist for projecting prevalence, each relying on different types of available data. As a result, projected estimates can differ according to the method and the look-back period used.[7] The analysis presented in this chapter used the Prevalence and Incidence Analysis Model [8] (see Analysis for details), which has been used in many other jurisdictions.

Conclusion

The anticipated growth in cancer prevalence in Ontario is similar to findings from other modelling studies in the United States [5] and in the United Kingdom [9]. Because many cancer survivors are expected to live long after their diagnosis, it is important to consider the impact of cancer and its treatment, recurrence and subsequent cancers, psychosocial care and other important effects that survivors may experience.[6]

The projected statistics presented in this chapter can be useful for health system planners, health providers and social service providers when planning for the unique healthcare needs and challenges of the growing number of people living with and after recovering from cancer.

 

References

  1. Government of Ontario Ministry of Finance. Ontario Population Projections, 2020–2046 [Internet]. Queen’s Printer for Ontario; 2021 [cited 2021 Jul 20]. Available from: https://www.ontario.ca/page/ontario-population-projections
  2. Gotay CC, Ransom S, Pagano IS. Quality of life in survivors of multiple primary cancers compared with cancer survivor controls. Cancer. 2007;110(9):2101–9.
  3. DeSantis CE, Lin CC, Mariotto AB, Siegel RL, Stein KD, Kramer JL, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin. 2014;64(4):252–71.
  4. Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010-2020. J Natl Cancer Inst. 2011;103(2):117–28.
  5. de Moor JS, Mariotto AB, Parry C, Alfano CM, Padgett L, Kent EE, et al. Cancer Survivors in the United States: Prevalence across the Survivorship Trajectory and Implications for Care. Cancer Epidemiol Biomarkers Prev. 2013;22(4):561–70.
  6. Yabroff KR, Bradley C, Tina Shih YC. Understanding financial hardship among cancer survivors in the United States: Strategies for prevention and mitigation. J Clin Oncol. 2020;38(4):292–301.
  7. Maddams J, Brewster D, Gavin A, Steward J, Elliott J, Utley M, et al. Cancer prevalence in the United Kingdom: Estimates for 2008. Br J Cancer. 2009;101(3):541–7.
  8. Verdecchia A, De Angelis G, Capocaccia R. Estimation and projections of cancer prevalence from cancer registry data. Stat Med. 2002;21(22):3511–26.
  9. Maddams J, Utley M, Moller H. Projections of cancer prevalence in the United Kingdom, 2010-2040. Br J Cancer. 2012;107(7):1195–202.