goserelin
Other Name: Zoladex®, Zoladex® LA
- For treating prostate cancer either alone or combined with other medications
- For treating cancers of the breast
- Also used for treating certain non-cancer conditions
- Tell your doctor if you have/had significant medical condition(s), especially if you have / had problems passing urine, weakness in your legs, severe osteoporosis, heart problems (including irregular heartbeat), diabetes, or have any allergies.
- Patients who have cancer are at a higher risk of developing blood clots. Some cancer drug treatments may increase this risk. Discuss this with your doctor.
- This drug may harm or affect the growth of embryos/offspring of animals exposed to it.
- While this may not be directly applicable to you, if there is ANY chance that you/your partner may become pregnant, you and your partner together must: ► Use 2 effective forms of birth control at the same time while taking this drug. Do not use birth control pills if you have breast cancer. Keep using birth control until 6 months after the last dose. Discuss with your healthcare team.
- Tell your doctor right away if you or your partner becomes pregnant.
- Do not breastfeed while taking this drug.
- Effects on Fertility: Probable
- Effects on Fertility: Probable
- This drug is given by injection under the skin. Various dosing schedules are used - check with your health care professional about how often you are given this medication.
- Be sure to visit your doctor for your repeat injection. Speak to your health care professional to see what drugs and supplies you need to bring for your next visit.
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Make sure your health care team knows about all your medications (prescription, over-the-counter, herbals and supplements). Check with your health care team before starting or stopping any of them.
- Store this drug at cool room temperature or in the refrigerator (no warmer than 25°C/77°F). Do not freeze. Protect from light and moisture.
- Keep out of reach of children and pets.
- Do not throw out any unused drugs at home. Bring them to your pharmacy for safe disposal.
The following side effects are common or severe. You may not have all of the side effects. Other side effects may occur. If you have any unusual or bothersome symptoms, discuss with your doctor.
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Diarrhea
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Contact your health care team if no improvement or if severe | ||||
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High (more common) or low blood pressure Severe headache, severe dizziness, fainting
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Contact your health care team if no improvement or if severe | ||||
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Symptoms of having low testosterone levels (in men)
Symptoms of having low estrogen levels (in women)
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Contact your health care team if no improvement or if severe | ||||
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Trouble with falling asleep
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Contact your health care team if no improvement or if severe | ||||
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Flare of symptoms of your prostate cancer (increased pain at tumour area, severe bone pain, severe back pain and/or weakness in the legs, difficulty passing urine or poor bladder/bowel control) Flare of symptoms of your breast cancer (increased pain at tumour area, severe bone pain)
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Get emergency medical help right away | ||||
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Heart problems (irregular heartbeat, chest pain, fainting, swelling in legs/ankles/belly, shortness of breath) |
Get emergency medical help right away | ||||||
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Abnormal liver lab tests
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Contact your health care team if no improvement or if severe | ||||||
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Blockage of an artery (blood vessel) in your heart, brain, chest, belly, or limbs; this may result in stroke (sudden loss of vision, speech, or the use of your limb(s)) or heart attack (chest pain, shortness of breath), or pain in chest, belly or limb |
Get emergency medical help right away | ||||||
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Blood clot (limb pain or swelling, hardened vein in limb), may occur in lungs (sudden start of coughing, breathing problems, chest pain, coughing blood) |
Get emergency medical help right away | ||||||
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Eye problems |
Contact your health care team as soon as possible (office hours) | ||||||
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High blood sugar (increased thirst, urinates frequently)
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Contact your health care team as soon as possible (office hours) | ||||||
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Allergic reaction (fever, severe rash, itchiness, swollen face, lip or tongue, chest or throat tightness; may occur during or shortly after the drug is given) |
Get emergency medical help right away | ||||||
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Unusual changes in personality, mood (for example, depression) or disordered thoughts |
Contact your health care team if no improvement or if severe | ||||||
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Bone pain; Bone loss |
Contact your health care team if no improvement or if severe | ||||||
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Bleeding or blood flow problems in the pituitary gland (sudden severe headache, vision changes, loss of consciousness) |
Get emergency medical help right away | ||||||
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Reactions at the injection site (redness, itchiness, bruising, mild rash or swelling) Injection site injury (pain, bleeding, bruising after injection, may be severe) |
Contact your health care team if no improvement or if severe | ||||||
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Kidney problems |
Get emergency medical help right away | ||||||
For more links on how to manage your symptoms go to https://www.cancercareontario.ca/en/symptom-management.
The information set out in the medication information sheets, regimen information sheets, and symptom management information (for patients) contained in the Drug Formulary (the "Formulary") is intended to be used by health professionals and patients for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or side effects of a certain drug, nor should it be used to indicate that use of a particular drug is safe, appropriate or effective for a given condition.
A patient should always consult a healthcare provider if he/she has any questions regarding the information set out in the Formulary. The information in the Formulary is not intended to act as or replace medical advice and should not be relied upon in any such regard. All uses of the Formulary are subject to clinical judgment and actual prescribing patterns may not follow the information provided in the Formulary.