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Guidelines & Advice
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Radiotherapy with Curative Intent in Patients with Early Stage, Medically Inoperable, Non-Small Cell Lung Cancer

ID: 7-21 May 2016
Type of Content: Guidelines & Advice, Clinical
Document Status: In-Review
Authors:
C.B. Falkson, E. Vella, E. Yu, M. El-Mallah, Y.C. Ung, P.M. Ellis, R. Mackenzie

Guideline Objective

To investigate the effectiveness of radiotherapy with curative intent in patients with early stage non-small cell lung cancer (NSCLC) who are medically inoperable.

Patient Population

Adult patients with potentially curable, early stage (Stage I or II) NSCLC (without nodal involvement or metastases), and who are deemed medically inoperable or refuse surgery.

Intended Guideline Users

Radiation planning and treatment providers, oncologists, thoracic surgeons, respirologists, diagnostic assessment groups, and other healthcare providers involved with lung cancer.

NOTE: Stereotactic body radiation therapy (SBRT) and stereotactic ablative radiation therapy are considered synonymous for the purposes of this guideline and will be referred to as SBRT from this point on.

Research Question(s)

  1. What is the effectiveness of radiotherapy with curative intent in patients with early stage NSCLC who are unable to undergo surgery?
  2. What are the most effective dose/fractionation schedules for curative intent radiotherapy?
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