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Liver Resection for Colorectal Metastases

ID: 17-7 Jun 2012
Type of Content: Guidelines & Advice, Clinical
Document Status: Current
Authors:
S. Gallinger, J.J. Biagi, G.G. Fletcher, C. Nhan, L. Ruo, R.S. McLeod , Liver Resection for Colorectal Metastases Expert Panel

Patient Population

Patients with liver metastases from CRC who have had or will have an complete (R0) resection of the primary cancer and who are being considered for resection of the liver or liver plus extrahepatic metastasis with curative intent.

Intended Guideline Users

Surgeons and medical oncologists dealing with CRC patients with liver metastases.

Research Question(s)

  1. Should surgery be considered for colorectal cancer (CRC) patients who have liver metastases plus (a) pulmonary metastases, (b) portal nodal disease, or (c) other extrahepatic metastases (EHM)?
  2. What is the role of chemotherapy in the surgical management of CRC with liver metastases in (a) patients with resectable disease in the liver, or (b) patients with initially unresectable disease in the liver that is downsized with chemotherapy (conversion)?
  3. What is the role of liver resection when one or more CRC liver metastases have radiographic complete response (RCR) following chemotherapy?
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