cabazitaxel
Other Name: Jevtana TM
mixed into larger bags of fluids
For treating a certain type of prostate cancer
Tell your doctor and pharmacist if you have or had significant medical condition(s), especially if you have or had:
- blood disorders such an anemia,
- nerve problems (numbness or tingling in fingers and toes),
- heart, kidney or liver problems,
- or any allergies.
- People with cancer have a higher risk of getting other cancers or developing blood clots. Some cancer medications may increase these risks, especially if used for a long period of time. Discuss any concerns about this medication with your health care team.
- The use of this medication in men with female partners may cause harm to the unborn baby if pregnancy occurs. Let your health care team know if your partner is pregnant, becomes pregnant during treatment, or is breastfeeding.
- While this may not be directly applicable to you, if there is ANY chance that your partner may become pregnant, you and your partner together must:
- ► Use 2 effective forms of birth control at the same time while taking this drug: Keep using birth control until 6 months after the last dose. Discuss with your healthcare team.
- This medication may affect fertility (ability for your partner to get pregnant)
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This drug is given by injection into a vein.
- You will be given drug(s) before cabazitaxel to prevent a reaction.
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This medication can interact with other medications and can result in the treatment not working as well or cause severe side effects.
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Make sure your health care team knows about all your medications (prescription, over-the-counter, herbals and supplements). Check with your health care team before starting or stopping any of them.
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Do not eat or drink grapefruit, starfruit, Seville oranges or their juices (or products that contain these) while on this treatment. They may increase side effects.
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For mild aches and pain or fever:
- If you feel unwell, take your temperature before taking any medications for pain or fever. They may hide a fever.
- You may take acetaminophen (Tylenol®) tablets. Ask your health care team about the right dose for you.
- Ibuprofen (Advil®, Motrin®), naproxen (Aleve®) or aspirin (acetylsalicylic acid, ASA), including low dose aspirin for heart conditions, may increase your chance of bleeding. Talk to your health care team before you start or stop these medications.
- Talk to your health care team or go to the closest emergency room right away if you have a fever. See the Fever pamphlet for more information.
- If you feel unwell, take your temperature before taking any medications for pain or fever. They may hide a fever.
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Drinking alcohol and smoking during your treatment may increase some side effects and make your medication less effective. Speak to your health care team about smoking and drinking alcohol while on treatment.
You may not have all of the side effects below. You may have side effects that are not listed.
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Unusual bleeding or bruising Fever, chills, infection You have a fever if your temperature taken in your mouth (oral temperature) is:
While you are getting treatment:
If you have a fever, talk to your health care team or go to the closest emergency room. |
Get emergency medical help right away | ||||
Diarrhea (may be severe) If you have diarrhea :
See the Diarrhea pamphlet for more information. |
Contact your health care team if no improvement or if severe | ||||
Fatigue (tiredness)
See our Fatigue pamphlet for more information. |
Contact your health care team if no improvement or if severe | ||||
Nausea and vomiting May occur in hours to days after your treatment. It is easier to prevent nausea than to treat it if it happens. To help prevent nausea:
If you have nausea or vomiting:
Also see Nausea & Vomiting pamphlet for more information. |
Contact your healthcare team if nausea lasts more than 48 hours or vomiting lasts more than 24 hours |
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Constipation To help prevent constipation :
To help treat constipation :
See the Constipation Pamphlet for more information. |
Contact your health care team if no improvement or if severe | ||||
Low appetite
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Contact your health care team if no improvement or if severe | ||||
Mild joint, muscle pain or cramps
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Contact your health care team if no improvement or if severe |
Other rare, but serious side effects are possible.
If you experience ANY of the following, speak to your cancer health care provider or get emergency medical help right away:
- Irregular heartbeat, shortness of breath, chest pain, fainting spells or swelling in your legs, ankles and belly; low blood pressure, dizziness
- Lower back pain, swelling, pee less than usual and have unusual weight gain
- Yellowish skin or eyes, unusually dark pee or pain on the right side of your belly
- Sudden, severe belly pain, bloating
- Difficulty breathing, chest pain or coughing up blood
- Pain, swelling and hardening of the vein in an arm or leg
- Signs of an allergy such as fever, itchiness, rash, swollen lips, face or tongue, chest and throat tightness
Who do I contact if I have questions or need help?My cancer health care provider is: ______________________________________________ During the day I should contact:________________________________________________ Evenings, weekends and holidays:______________________________________________
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Other Notes:
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May 2021 Updated "What is this medication for" section
For more links on how to manage your symptoms go to www.cancercareontario.ca/symptoms.
The information set out in the medication information sheets, regimen information sheets, and symptom management information (for patients) contained in the Drug Formulary (the "Formulary") is intended to be used by health professionals and patients for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or side effects of a certain drug, nor should it be used to indicate that use of a particular drug is safe, appropriate or effective for a given condition.
A patient should always consult a healthcare provider if he/she has any questions regarding the information set out in the Formulary. The information in the Formulary is not intended to act as or replace medical advice and should not be relied upon in any such regard. All uses of the Formulary are subject to clinical judgment and actual prescribing patterns may not follow the information provided in the Formulary.