mitoXANTRONE
Other Name: Generic brand(s) available, Novantrone®
; may be mixed into larger bags of fluids
- For treating breast cancer that has spread to other parts of the body, blood cancers such as leukemias an lymphomas, liver cancer and prostate cancer.
- Tell your doctor if you have/had significant medical condition(s), especially if you have / had heart disease, or any allergies.
- MitoXANTrone may harm the unborn baby.
- Let your doctor know if you are breastfeeding, pregnant or plan to become pregnant
- People who have cancer or leukemia are at a higher risk of developing other cancers/leukemias (usually some years later). Some cancer medications may increase these risks, especially if used for a prolonged period of time. You should discuss any concerns about this drug with your doctor.
- Do not use mitoXANTrone if you are pregnant. If there is ANY chance that you or your partner may become pregnant, you and your partner together must:►Use 2 effective forms of birth control at the same time while on mitoXANTrone. Do not take birth control pills if you have breast cancer. Keep using birth control until 6 months after the last dose (general recommendation). Discuss with your healthcare team.
- Tell your doctor right away if you or your partner becomes pregnant.
- Do not breastfeed while on mitoXANTtrone treatment. Breastfeeding should be discontinued prior to mitoXANTrone treatment.
- Effects on Fertility: Unknown
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This drug is given by injection into a vein.
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This medication can interact with other medications and can result in the treatment not working as well or cause severe side effects.
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Make sure your health care team knows about all your medications (prescription, over-the-counter, herbals and supplements). Check with your health care team before starting or stopping any of them.
- Your urine may turn blue-green for 1-2 days after receiving mitoxantrone.
The following side effects are common or severe. You may not have all of the side effects. Other side effects may occur. If you have any unusual or bothersome symptoms, discuss with your doctor.
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Liver problems |
Get emergency medical help right away | ||||
Hair thinning or loss
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Diarrhea
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Contact your health care team if no improvement or if severe | ||||
Tiredness
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Contact your health care team if no improvement or if severe | ||||
Mouth sores
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Contact your health care team as soon as possible | ||||
Unusual bleeding or bruising You may have black stools, cough up blood, blood in your urine, purple or red dots on your skin or bleeding that will not stop. Fever, chills, infection You have a fever if your temperature taken in your mouth (oral temperature) is:
While you are getting chemotherapy treatments:
If you have a fever, talk to your health care team or go to the closest emergency room. |
Get emergency medical help right away | ||||
Nausea and vomiting
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Contact your health care team if no improvement or if severe | ||||
Pain, burning, redness, or swelling on skin where drug was injected
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Get emergency medical help right away |
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Allergic reaction
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Get emergency medical help right away | ||||||
Heart problems |
Get emergency medical help right away | ||||||
Lung problems |
Get emergency medical help right away | ||||||
Loss of consciousness, seizures, confusion |
Get emergency medical help right away | ||||||
Rapid killing of cancer cells when you start treatment may lead to build up of cell waste products
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Get emergency medical help right away |
For more links on how to manage your symptoms go to www.cancercareontario.ca/symptoms.
The information set out in the medication information sheets, regimen information sheets, and symptom management information (for patients) contained in the Drug Formulary (the "Formulary") is intended to be used by health professionals and patients for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or side effects of a certain drug, nor should it be used to indicate that use of a particular drug is safe, appropriate or effective for a given condition.
A patient should always consult a healthcare provider if he/she has any questions regarding the information set out in the Formulary. The information in the Formulary is not intended to act as or replace medical advice and should not be relied upon in any such regard. All uses of the Formulary are subject to clinical judgment and actual prescribing patterns may not follow the information provided in the Formulary.