medroxyprogesterone
Other Name: Provera® (Pfizer)
In various strengths, shapes and colours
- For treating breast or endometrial cancer.
- Tell your doctor and pharmacist if you have/had significant medical condition(s), especially if you have / had liver disease, heart problems, eye problems, abnormal vaginal bleeding, diabetes, or any allergies.
- People who have cancer or leukemia are at a higher risk of developing other cancers/leukemias (usually some years later) or blood clots. Some cancer medications may increase these risks, especially if used for a prolonged period of time. You should discuss any concerns with your doctor.
- This drug contains a small amount of lactose. If you cannot tolerate lactose, talk to your doctor or pharmacist.
- Medroxyprogesterone can harm the unborn baby and should not be used by pregnant women.
- If there is ANY chance that you may become pregnant, you and your partner together must:
► Use 2 effective forms of birth control at the same time while receiving this drug. Do not take birth control pills if you have breast cancer. Keep using birth control until at least 6 months after the last dose (general recommendation). Discuss with your healthcare team.
- Tell your doctor right away if you become pregnant
- Do not breastfeed while using this drug.
- Effects on Fertility: Unlikely
- Effects on Fertility: Unlikely
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Swallow whole with a glass of water, with or without food.
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Take the dose at about the same time each day.
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If you miss a dose, take it if it is within 12 hours from the missed dose, otherwise skip and take your next dose as scheduled. Do not double the dose to make up for the forgotten one.
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This medication can interact with other medications and can result in the treatment not working as well or cause severe side effects.
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Make sure your health care team knows about all your medications (prescription, over-the-counter, herbals and supplements). Check with your health care team before starting or stopping any of them.
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Keep this medication in the original packaging at room temperature in a dry place, away from heat and light. Keep out of sight and reach of children and pets.
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Do not throw out any unused medications at home. Bring them to your pharmacy to be thrown away safely.
The following side effects are common or severe. You may not have all of the side effects listed, while others not on this list may also occur. Discuss with your doctor if you have any unusual or bothersome symptoms.
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Headache; mild joint, muscle pain or cramps
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Contact your health care team if no improvement or if severe | ||||
Pains or cramps in the belly, bloating
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Contact your health care team if no improvement or if severe | ||||
Mild swelling in arms and legs; puffiness
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Contact your health care team if no improvement or if severe | ||||
Vaginal bleeding and symptoms of having low estrogen levels
Symptoms of having low testosterone levels
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Contact your health care team if no improvement or if severe |
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Blockage of an artery (blood vessel) in your heart, brain, chest, belly, or limbs; this may result in stroke (sudden loss of vision, speech, or the use of your limb(s)) or heart attack (chest pain, shortness of breath), or pain in chest, belly or limb | Get emergency medical help right away | ||||||
Blood clot (limb pain or swelling, hardened vein in limb), may occur in lungs (sudden start of coughing, breathing problems, chest pain, coughing blood) | Get emergency medical help right away | ||||||
Heart problems |
Get emergency medical help right away | ||||||
Allergic reaction (fever, severe rash, itchiness, swollen face, lip or tongue, chest or throat tightness; may occur during or shortly after the drug is given) |
Get emergency medical help right away | ||||||
Bone fractures
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Contact your health care team if no improvement or if severe | ||||||
Eye problems |
Contact your health care team as soon as possible (office hours) |
For more links on how to manage your symptoms go to https://www.cancercareontario.ca/en/symptom-management.
The information set out in the medication information sheets, regimen information sheets, and symptom management information (for patients) contained in the Drug Formulary (the "Formulary") is intended to be used by health professionals and patients for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or side effects of a certain drug, nor should it be used to indicate that use of a particular drug is safe, appropriate or effective for a given condition.
A patient should always consult a healthcare provider if he/she has any questions regarding the information set out in the Formulary. The information in the Formulary is not intended to act as or replace medical advice and should not be relied upon in any such regard. All uses of the Formulary are subject to clinical judgment and actual prescribing patterns may not follow the information provided in the Formulary.