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31 Results
Guidelines and Advice
Status: In-Review
ID: 19-6
Apr 2016
Drug
Other Name(s): Xgeva®; Wyost™; Osenvelt™
Quick Link(s): Drug Monograph, Patient Info Sheet
Dec 2025
Regimen
Cancer Type:
Breast, 
Central Nervous System, 
Endocrine, 
Adrenal, 
Neuroendocrine, 
Pancreatic Neuroendocrine, 
Parathyroid, 
Thymoma, 
Thyroid, 
Gastrointestinal, 
Anus, 
Colorectal, 
Esophagus, 
Gastric / Stomach, 
Gastrointestinal Stromal Tumours, 
Hepatobiliary / Liver / Bile Duct, 
Mesothelioma (Peritoneal), 
Neuroendocrine (GI), 
Pancreas, 
Rectal, 
Small bowel and appendix, 
Genitourinary, 
Bladder / Urothelial, 
Penile, 
Prostate, 
Renal cell / Kidney, 
Testis, 
Gynecologic, 
Cervix, 
Endometrial, 
Germ Cell, 
Gestational Trophoblastic Disease, 
Ovary, 
Uterine Sarcoma, 
Vagina, 
Vulva, 
Head and Neck, 
Larynx, 
Nasopharynx, 
Oral, 
Paranasal Sinus, 
Pharynx, 
Salivary Gland, 
Squamous Cell, 
Kaposi's Sarcoma, 
Lung, 
Mesothelioma (Pleural), 
Neuroendocrine (Lung), 
Non-Small Cell, 
Small Cell, 
Mesothelioma, 
Ocular / Eye, 
Sarcoma, 
Desmoid Tumour, 
Ewing's, 
Ewing's and Soft Tissue, 
GIST, 
Giant Cell Tumour, 
Kaposi's Sarcoma, 
Osteogenic / Bone, 
Soft Tissue, 
Uterine, 
Wilm's Tumour, 
Skin, 
Basal Cell, 
Melanoma, 
Merkel Cell, 
Squamous Cell, 
Unknown Primary
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Intent: Palliative
Funding:
New Drug Funding Program
    Pembrolizumab (Adult and Pediatric) - Unresectable or Metastatic MSI-H or dMMR Advanced Solid Tumours
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Drugs Used:
pembrolizumab
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Quick Link(s):
Regimen Monograph
Sep 2025
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
CISplatin
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Quick Link(s):
Regimen Monograph
Nov 2024
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
PACLitaxel
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Quick Link(s):
Regimen Monograph
Nov 2024
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
PACLitaxel
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Quick Link(s):
Regimen Monograph
Nov 2024
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
DOXOrubicin
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Quick Link(s):
Regimen Monograph
Oct 2023
Regimen
Cancer Type:
Breast, 
Genitourinary, 
Renal cell / Kidney, 
Lung, 
Non-Small Cell, 
Small Cell, 
Unknown Primary
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Intent: Palliative
Drugs Used:
denosumab (Unfunded)
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Quick Link(s):
Regimen Monograph
Aug 2024
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
EPIrubicin,
CISplatin,
fluorouracil
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Quick Link(s):
Regimen Monograph
Apr 2023
Regimen
Cancer Type:
Central Nervous System, 
Gastrointestinal, 
Colorectal, 
Esophagus, 
Gastric / Stomach, 
Hepatobiliary / Liver / Bile Duct, 
Pancreas, 
Genitourinary, 
Bladder / Urothelial, 
Prostate, 
Head and Neck, 
Lung, 
Small Cell, 
Unknown Primary
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Intent: Palliative
Drugs Used:
CARBOplatin,
etoposide
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Quick Link(s):
Regimen Monograph
Dec 2023
Regimen
Cancer Type:
Unknown Primary
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Intent: Palliative
Drugs Used:
CARBOplatin
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Quick Link(s):
Regimen Monograph
Nov 2019
Regimen
Cancer Type:
Breast, 
Central Nervous System, 
Endocrine, 
Adrenal, 
Neuroendocrine, 
Pancreatic Neuroendocrine, 
Parathyroid, 
Thymoma, 
Thyroid, 
Gastrointestinal, 
Anus, 
Colorectal, 
Esophagus, 
Gastric / Stomach, 
Gastrointestinal Stromal Tumours, 
Hepatobiliary / Liver / Bile Duct, 
Mesothelioma (Peritoneal), 
Neuroendocrine (GI), 
Pancreas, 
Rectal, 
Small bowel and appendix, 
Genitourinary, 
Bladder / Urothelial, 
Penile, 
Prostate, 
Renal cell / Kidney, 
Testis, 
Gynecologic, 
Cervix, 
Endometrial, 
Germ Cell, 
Gestational Trophoblastic Disease, 
Ovary, 
Uterine Sarcoma, 
Vagina, 
Vulva, 
Head and Neck, 
Larynx, 
Nasopharynx, 
Oral, 
Paranasal Sinus, 
Pharynx, 
Salivary Gland, 
Squamous Cell, 
Kaposi's Sarcoma, 
Lung, 
Mesothelioma (Pleural), 
Neuroendocrine (Lung), 
Non-Small Cell, 
Small Cell, 
Sarcoma, 
Desmoid Tumour, 
Ewing's, 
Ewing's and Soft Tissue, 
GIST, 
Giant Cell Tumour, 
Kaposi's Sarcoma, 
Osteogenic / Bone, 
Soft Tissue, 
Uterine, 
Wilm's Tumour, 
Skin, 
Basal Cell, 
Melanoma, 
Merkel Cell, 
Squamous Cell, 
Unknown Primary
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Intent: Palliative
Funding:
Exceptional Access Program
    larotrectinib - For the treatment of unresectable locally advanced, or metastatic solid tumours with neurotrophic tyrosine receptor kinase (NTRK) gene fusion, according to clinical criteria
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Drugs Used:
larotrectinib
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Quick Link(s):
Regimen Monograph
Sep 2025

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