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Magnetic Resonance Imaging for Pre-Treatment Local Staging of Prostate Cancer

ID: 27-3 Mar 2016
Type of Content: Guidelines & Advice, Clinical
Document Status: In-Review
Authors:
M. Haider, J. Salerno, A. Finelli, C. Morash, N. Power, N. Schieda, Magnetic Resonance Imaging in the Pre-Treatment Staging of Prostate Cancer Guideline Development Group

Guideline Objective

To make recommendations with respect to the use of T2-weighted magnetic resonance imaging (MRI) ± functional sequences in the pre-treatment local staging of patients with newly diagnosed prostate cancer.

Patient Population

Men with newly diagnosed biopsy-confirmed prostate cancer who are under consideration for radical treatment.

Intended Guideline Users

Clinicians who are involved in the staging and treatment of prostate cancer patients.

Research Question(s)

  1. What is the performance and diagnostic accuracy of MRI ± DCE, DWI, MRS in men with newly diagnosed biopsy-confirmed prostate cancer who are under consideration for radical treatment?
  2. What is the impact of pre-treatment local staging by MRI ± DCE, DWI, MRS on patient outcomes, biochemical recurrence, changes in treatment planning (including nervesparing surgery), changes in stage classification, and surgical margin status in men with newly diagnosed biopsy-confirmed prostate cancer who are under consideration for radical treatment?
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