You are using an outdated browser. We suggest you update your browser for a better experience. Click here for update.
Close this notification.
Skip to main content Skip to search

COVID-19: Get the latest updates or take a self-assessment.

Published Research

A large body of research has been produced by scientists, clinical leads, scientific leads and/or staff working for or funded by Cancer Care Ontario. Much of the research has been published in peer-reviewed scientific journals.

For a list of research from across CCO, including articles about chronic kidney disease and other health related topics, visit PubMed.

Featured Cancer Research Articles

Araghi M, Arnold M, Rutherford MJ, Guren MG, Cabasag CJ, Bardot A, Ferlay J, Tervonen H, Shack L, Woods RR, Saint-Jacques N, De P, McClure C, Engholm G, Gavin AT, Morgan E, Walsh PM, Jackson C, Porter G, Møller B, Bucher O, Eden M, O'Connell DL, Bray F, Soerjomataram I. Colon and rectal cancer survival in seven high-income countries 2010-2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project). Gut. 2021 Jan;70(1):114-126. doi: 10.1136/gutjnl-2020-320625. Epub 2020 Jun 1. PMID: 32482683.

Buick C, Jembere N, Wang L, Kupets R. Cervical Screening and Colposcopy Management of Women Ages 24 and Under. Obstet Gynaecol Can. 2020 Dec;42(12):1518-1524. doi: 10.1016/j.jogc.2020.06.013. Epub 2020 Jul 1.

Cabasag CJ, Butler J, Arnold M, Rutherford M, Bardot A, Ferlay J, Morgan E, Møller B, Gavin A, Norell CH, Harrison S, Saint-Jacques N, Eden M, Rous B, Nordin A, Hanna L, Kwon J, Cohen PA, Altman AD, Shack L, Kozie S, Engholm G, De P, Sykes P, Porter G, Ferguson S, Walsh P, Trevithick R, O'Connell D, Bray F, Soerjomataram I. Exploring variations in ovarian cancer survival by age and stage (ICBP SurvMark-2): A population-based study. Gynecol Oncol. 2020 Apr;157(1):234-244. doi: 10.1016/j.ygyno.2019.12.047. Epub 2020 Jan 28. PMID: 32005583.

Cenin DR, Tinmouth J, Naber SK, Dubé C, McCurdy BR, Paszat L, Rabeneck L, Lansdorp-Vogelaar I.Calculation of Stop ages for Colorectal Cancer Screening Based on Comorbidities and Screening History. Clin Gastroenterol Hepatol. 2020 May 22:S1542-3565(20)30699-6. doi: 10.1016/j.cgh.2020.05.038. Epub ahead of print. PMID: 32450362.

Chan K, Nam S, Evans B, deOliveira C, Chambers A, Gavura S, Hoch J, Mercer RE, Dai WF, Beca J, Tadrous M, Isaranuwatchai W. Developing a framework to incorporate real-world evidence in cancer drug funding decisions: the Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration. BMJ Open. 2020 Jan 7;10(1):e032884. doi: 10.1136/bmjopen-2019-032884. PMID: 31915169.

Chang VC, Cotterchio M, Bondy SJ, Kotsopoulos J. Iron intake, oxidative stress-related genes and breast cancer risk. Int J Cancer. 2020 Sep 1;147(5):1354-1373. doi: 10.1002/ijc.32906. Epub 2020 Feb 25. PMID: 32022258.

Clark M, Jembere N, Wang L, Kupets R.Survival of Older Women With Cervical Cancer Based on Screening History. J Low Genit Tract Dis. 2021 Jan 1;25(1):9-14. doi: 10.1097/LGT.0000000000000582. PMID: 33347044.

Clemons M, Fergusson D, Simos D, Mates M, Robinson A, Califaretti N, Zibdawi L, Bahl M, Raphael J, Ibrahim MFK, Fernandes R, Pitre L, Aseyev O, Stober C, Vandermeer L, Saunders D, Hutton B, Mallick R, Pond GR, Awan A, Hilton J. A multicentre, randomised trial comparing schedules of G-CSF (filgrastim) administration for primary prophylaxis of chemotherapy-induced febrile neutropenia in early stage breast cancer. Ann Oncol. 2020 Jul;31(7):951-957. doi: 10.1016/j.annonc.2020.04.005. Epub 2020 Apr 20. PMID: 32325257. [received Cancer Care Ontario funding].

Dai WF, Beca J, Croxford R, Isaranuwatchai W, Menjak IB, Petrella TM, Mittmann N, Earle CC, Gavura S, Mercer RE, Hanna TP, Chan KKW. Real-world, population-based cohort study of toxicity and resource utilization of second-line ipilimumab for metastatic melanoma in Ontario, Canada. Int J Cancer. 2020 Oct 26. doi: 10.1002/ijc.33357. Epub ahead of print. PMID: 33105030.

Darling GE, Tammemägi MC, Schmidt H, Buchanan DN, Leung Y, McGarry C, Rabeneck L. Organized Lung Cancer Screening Pilot: Informing a Province-wide Program in Ontario, Canada. Ann Thorac Surg. 2020 Oct 8:S0003-4975(20)31623-4. doi: 10.1016/j.athoracsur.2020.07.051. Epub ahead of print. PMID: 33039364.

Dossa F, Dubé C, Tinmouth J, Sorvari A, Rabeneck L, McCurdy BR, Dominitz JA, Baxter NN. Practice recommendations for the use of sedation in routine hospital-based colonoscopy. BMJ Open Gastroenterol. 2020 Feb 16;7(1):e000348. doi: 10.1136/bmjgast-2019-000348. eCollection 2020. PMID: 32128226.

Forster K, Tsang K, Li S, Ieraci L, Murray P, Woltman KJ, Chmelnitsky D, Holloway CMB, Kennedy ED. Can concordance between actual care received and a pathway map be measured on a population level in Ontario? A pilot study. Curr Oncol. 2020 Feb;27(1):e27-e33. doi: 10.3747/co.27.5349. Epub 2020 Feb 1. PMID: 32218665.

Gupta S, Bharti B, Ahnen DJ, Buchanan DD, Cheng IC, Cotterchio M, Figueiredo JC, Gallinger SJ, Haile RW, Jenkins MA, Lindor NM, Macrae FA, Le Marchand L, Newcomb PA, Thibodeau SN, Win AK, Martinez ME. Potential impact of family history-based screening guidelines on the detection of early-onset colorectal cancer. Cancer. 2020 Jul 1;126(13):3013-3020. doi: 10.1002/cncr.32851. Epub 2020 Apr 20. PMID: 32307706.

Habbous S, Khan Y, Langer DL, Kaan M, Green B, Forster K, Darling G, Holloway CM. The effect of diagnostic assessment programs on the diagnosis and treatment of patients with lung cancer in Ontario, Canada. Ann Thorac Med. 2020;16(1):81. doi: 10.4103/atm.ATM_283_20.

Hagens V, Tassone C, Evans JM, Burns D, Simanovski V, Matheson G. From Measurement to Improvement in Ontario's Cancer System: Analyzing the Performance of 28 Provincial Indicators over 15 Years. Healthc Q. 2020 Apr;23(1):53-59. doi: 10.12927/hcq.2020.26138. PMID: 32249740.

Harris MA, MacLeod J, Kim J, Pahwa M, Tjepkema M, Peters P, Demers PA. Use of a Canadian Population-Based Surveillance Cohort to Test Relationships Between Shift Work and Breast, Ovarian, and Prostate Cancer. Ann Work Expo Health. 2020 Apr 30;64(4):387-401. doi: 10.1093/annweh/wxaa017. PMID: 32144413.

Jamal S, Sheppard AJ, Cotterchio M, Gallinger S. Association between known risk factors and colorectal cancer risk among Indigenous people participating in the Ontario Familial Colon Cancer Registry. Curr Oncol. 2020 Aug;27(4). doi: 10.3747/co.27.6039. PMID: 32905327.

Mbuya Bienge C, Pashayan N, Brooks JD, Dorval M, Chiquette J, Eloy L, Turgeon A, Lambert-Côté L, Paquette JS, Lévesque E, Hagan J, Walker MJ, Lapointe J, Dalpé G, Granados Moreno PG, Blackmore K, Wolfson M, Joly Y, Broeders M, Knoppers BM, Chiarelli AM, Simard J, Nabi H. Women's Views on Multifactorial Breast Cancer Risk Assessment and Risk-Stratified Screening: A Population-Based Survey from Four Provinces in Canada. J Pers Med. 2021 Feb 2;11(2):95. doi: 10.3390/jpm11020095. PMID: 33540785.

Norwood TA, Buajitti E, Lipscombe LL, Stukel TA, Rosella LC. Incidental detection, imaging modalities and temporal trends of differentiated thyroid cancer in Ontario: a population-based retrospective cohort study. CMAJ Open. 2020 Nov 2;8(4):E695-E705. doi: 10.9778/cmajo.20200095. PMID: 33139390.

Ruco A, Dossa F, Tinmouth J, Llovet D, Kishibe T, Baxter NN. Social media and mobile health technology for cancer screening: a systematic review and meta-analysis protocol. BMJ Open. 2020 Feb 5;10(2):e035411. doi: 10.1136/bmjopen-2019-035411. PMID: 32029500.

Sheppard AJ, Chiarelli AM, Hanley A, Marrett L. Influence of preexisting diabetes on survival after a breast cancer diagnosis in First Nations women in Ontario, Canada. J Glob Oncol. 2020 Feb;6:99-107. doi: 10.1200/JGO.19.00061. PMID: 32031452.

Stacey D, Jolicoeur L, Balchin K, Duke K, Ludwig C, Carley M, Jibb L, Kuziemsky C, Madore S, Rambout L, Romanick J, Vickers MM, Martelli L. Quality of telephone nursing services for adults with cancer and related non-emergent visits to the emergency department. Can Oncol Nurs J. 2020 Jul 1;30(3):193-199. doi: 10.5737/23688076303193199. PMID: 33118979. [received Cancer Care Ontario funding]

Swift BE, Wang L, Jembere N, Kupets R. Risk of Recurrence After Treatment for Cervical Intraepithelial Neoplasia 3 and Adenocarcinoma In Situ of the Cervix: Recurrence of CIN 3 and AIS of Cervix. J Low Genit Tract Dis. 2020 Jul;24(3):252-258. doi: 10.1097/LGT.0000000000000542. Epub 2020 May 6. PMID: 32384365.

Tinmouth J, Dong S, Stogios C, Rabeneck L, Rey M, Dubé C; ColonCancerCheck/Gastrointestinal Endoscopy COVID Working Group. Estimating the backlog of colonoscopy due to COVID-19 and comparing strategies to recover in Ontario, Canada. Gastroenterology. 2020 Dec 7:S0016-5085(20)35530-X. doi: 10.1053/j.gastro.2020.11.048. Epub ahead of print. PMID: 33301778.

Tobias JK, Tinmouth J, Senese LC, Jumah N, Llovet D, Kewayosh A, Rabeneck L, Dobrow M. Health Policy as a Barrier to First Nations Peoples' Access to Cancer Screening. Healthc Policy. 2020 Feb;15(3):28-46. doi: 10.12927/hcpol.2020.26132. PMID: 32176609.

Webber C, Whitehead M, Eisen A, Holloway CMB, Groome PA. Breast cancer diagnosis and treatment wait times in specialized diagnostic units compared with usual care: a population-based study. Curr Oncol. 2020 Aug;27(4):e377-e385. doi: 10.3747/co.27.6115. Epub 2020 Aug 1. PMID: 32905256.