COVID-19: Get the latest updates or take a self-assessment.

Published Research

A large body of research has been produced by scientists, clinical leads, scientific leads and/or staff working for or funded by Cancer Care Ontario. Much of the research has been published in peer-reviewed scientific journals.

For a list of research from across CCO, including articles about chronic kidney disease and other health related topics, visit PubMed.

Featured Cancer Research Articles

Chan K, Chan B, Linden K, Erler D, D'Alimonte L, Kong V, Kraus J, Harnett N. Framework Development: Standardizing Definition of Advanced Practice Radiation Therapy Activities for Clinical Workload Quantification. Tech Innov Patient Support Radiat Oncol. 2024 Jan 17;29:100238. doi: 10.1016/j.tipsro.2024.100238. PMID: 38426124.

Fu R, Tinmouth J, Li Q, Dare A, Hallet J, Coburn N, Lapointe-Shaw L, Look Hong NJ, Karam I, Rabeneck L, Krzyzanowska M, Sutradhar R, Eskander A. COVID-19 pandemic impact on the potential exacerbation of screening mammography disparities: A population-based study in Ontario, Canada. Prev Med Rep. 2023 Dec 25;37:102578. doi: 10.1016/j.pmedr.2023.102578. PMID: 38222304.

Hirpara DH, Irish J, Rashid M, Martin T, Zhu A, Hunter A, Jayaraman S, Wei AC, Coburn NG, Wright FC. Defining Standards for Hepatopancreatobiliary Cancer Surgery in Ontario, Canada: A Population-Based Cohort Study of Clinical Outcomes. J Am Coll Surg. 2023 Oct 5. doi: 10.1097/XCS.0000000000000885. Epub ahead of print. PMID: 37796140.

Jumah NA, Kewayosh A, Downey B, Campbell Senese L, Tinmouth J. Developing a Health Equity Impact Assessment 'Indigenous Lens Tool' to address challenges in providing equitable cancer screening for indigenous peoples. BMC Public Health. 2023 Nov 15;23(1):2250. doi: 10.1186/s12889-023-16919-7. PMID: 37968666.

Laskar RS, Qu C, Huyghe JR, Harrison T, Hayes RB, Cao Y, … Cotterchio M, et al. Genome-wide association study and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer. Ann Oncol. 2024 Feb 24:S0923-7534(24)00058-9. doi: 10.1016/j.annonc.2024.02.008. Epub ahead of print. PMID: 38408508.

McPhail S, Barclay ME, Johnson SA, Swann R, Alvi R, Barisic A, Bucher O, Creighton N, Denny CA, Dewar RA, Donnelly DW, Dowden JJ, Downie L, Finn N, Gavin AT, Habbous S, Huws DW, May L, McClure CA, Møller B, Musto G, Nilssen Y, Saint-Jacques N, Sarker S, Shack L, Tian X, Thomas RJS, Thomson CS, Wang H, Woods RR, You H, Lyratzopoulos G; ICBP Module 9 Chemotherapy Group. Use of chemotherapy in patients with oesophageal, stomach, colon, rectal, liver, pancreatic, lung, and ovarian cancer: an International Cancer Benchmarking Partnership (ICBP) population-based study. Lancet Oncol. 2024 Mar;25(3):338-351. doi: 10.1016/S1470-2045(24)00031-7. PMID: 38423048. [ICBP Module 9 Chemotherapy Group member Katharina Forster]

McPhail S, Barclay ME, Swann R, Johnson SA, Alvi R, Barisic A, Bucher O, Creighton N, Denny CA, Dewar RA, Donnelly DW, Dowden JJ, Downie L, Finn N, Gavin AT, Habbous S, Huws DW, Kumar SE, May L, McClure CA, Morrison DS, Møller B, Musto G, Nilssen Y, Saint-Jacques N, Sarker S, Shack L, Tian X, Thomas RJ, Wang H, Woods RR, You H, Zhang B, Lyratzopoulos G; ICBP Module 9 Radiotherapy Group. Use of radiotherapy in patients with oesophageal, stomach, colon, rectal, liver, pancreatic, lung, and ovarian cancer: an International Cancer Benchmarking Partnership (ICBP) population-based study. Lancet Oncol. 2024 Mar;25(3):352-365. doi: 10.1016/S1470-2045(24)00032-9. PMID: 38423049. [ICBP Module 9 Radiotherapy Group members Katharina Forster, Bo Green, Eric Gutierrez, and Dr. Jason Pantarotto]

Mittmann N, Blackmore KM, Seung SJ, Diong C, Done SJ, Chiarelli AM. Healthcare and Cancer Treatment Costs of Breast Screening Outcomes among Higher than Average Risk Women. Curr Oncol. 2023 Sep 18;30(9):8550-8562. doi: 10.3390/curroncol30090620. PMID: 37754535.

Nicolau IA, Moineddin R, Antoniou T, Brooks JD, Gillis JL, Kendall CE, Cooper C, Cotterchio M, Salters K, Smieja M, Kroch AE, Lindsay JD, Price C, Mohamed A, Burchell AN. Trends in infection-related and infection-unrelated cancer incidence among people with and without HIV infection in Ontario, Canada, 1996-2020: a population-based matched cohort study using health administrative data. CMAJ Open. 2023 Oct 10;11(5):E894-E905. doi: 10.9778/cmajo.20220230. PMID: 37816545.

Piedimonte S, Tsang K, Jembere N, Murphy J, Karapetian T, Gao J, McCurdy B, Sacco J, Kupets R. Defining the Longitudinal Risk of CIN 3+ for< CIN 2 Colposcopy for Patients Referred With High-Grade Cytology. J Low Genit Tract Dis. 2023 Oct 30. doi: 10.1097/LGT.0000000000000765. Epub ahead of print. PMID: 37906611.

Rzadki K, Baqri W, Yermakhanova O, Habbous S, Das S. Choreographed expansion of services results in decreased patient burden without compromise of outcomes: An assessment of the Ontario experience. Neuro-Oncology Practice. 2023 Dec 14:npad076.

Sritharan J, Christopher G, Eros FR, Demers PA. Exploring sex differences in lung cancer risk among workers in Ontario, Canada's Occupational Disease Surveillance System. Front Environ Health. 2023 Dec;2:1325197. doi: 10.3389/fenvh.2023.1325197.

Sritharan J, Demers PA, Eros FR, Berriault C, Dakouo M, Kirkham TL. Cancer risks among emergency medical services workers in Ontario, Canada. Prehosp Emerg Care. 2023 Nov 15:1-9. doi: 10.1080/10903127.2023.2283079. Epub ahead of print. PMID: 37967276.

Swift BE, Mazuryk J, Yermakhanova O, Green B, Ferguson SR, Kupets R. Access to surgery for endometrial cancer patients during the COVID-19 pandemic in Ontario, Canada: a population-based study. J Obstet Gynaecol Can. 2023 Sep 22:102226. doi: 10.1016/j.jogc.2023.102226. Epub ahead of print. PMID: 37742834.

Featured Renal Disease Articles

Bhasin AA, Molnar AO, McArthur E, Nash DM, Busse JW, Cooper R, Heale E, Ip J, Pang J, Blake PG, Garg AX, Kurdyak P, Kim SJ, Sultan H, Walsh M. Mental health and addiction service utilization among people living with chronic kidney disease. Nephrol Dial Transplant. 2023 Nov 28:gfad240. doi: 10.1093/ndt/gfad240. Epub ahead of print. PMID: 38017620.

Enilama O, Yau K, Er L, Atiquzzaman M, Oliver MJ, Romney MG, Leis JA, Abe KT, Qi F, Colwill K, Gingras AC, Hladunewich MA, Levin A. Humoral Response Following 3 Doses of mRNA COVID-19 Vaccines in Patients With Non-Dialysis-Dependent CKD: An Observational Study. Can J Kidney Health Dis. 2024 Jan 29;11:20543581231224127. doi: 10.1177/20543581231224127. PMID: 38292817.

Garg AX, Yohanna S, Naylor KL, McKenzie SQ, Mucsi I, Dixon SN, Luo B, Sontrop JM, Beaucage M, Belenko D, Coghlan C, Cooper R, Elliott L, Getchell L, Heale E, Ki V, Nesrallah G, Patzer RE, Presseau J, Reich M, Treleaven D, Wang C, Waterman AD, Zaltzman J, Blake PG. Effect of a Novel Multicomponent Intervention to Improve Patient Access to Kidney Transplant and Living Kidney Donation: The EnAKT LKD Cluster Randomized Clinical Trial. JAMA Intern Med. 2023 Nov 3. doi: 10.1001/jamainternmed.2023.5802. Epub ahead of print. PMID: 37922156.

Molnar AO, Nash DM, Emblem J, Bota S, McArthur E, Luo B, Liu Y, Garg AX, Blake PG, Brimble KS. Patient Care Gaps Prior to Maintenance Dialysis Initiation: A Population-Based Retrospective Study. Can J Kidney Health Dis. 2023 Nov 17;10:20543581231212134. doi: 10.1177/20543581231212134. PMID: 38020481.

Wang C, Garg AX, Luo B, Kim SJ, Knoll G, Yohanna S, Treleaven D, McKenzie S, Ip J, Cooper R, Elliott L, Naylor KL. Defining pre-emptive living kidney donor transplantation as a quality indicator. Am J Transplant. 2024 Feb 21:S1600-6135(24)00159-X. doi: 10.1016/j.ajt.2024.02.017. Epub ahead of print. PMID: 38395149.

Yau K, Kurtesi A, Qi F, Delgado-Brand M, Tursun TR, Hu Q, Dhruve M, Kandel C, Enilama O, Levin A, Jiang Y, Hardy WR, Yuen DA, Perl J, Chan CT, Leis JA, Oliver MJ, Colwill K, Gingras AC, Hladunewich MA. Omicron variant neutralizing antibodies following BNT162b2 BA.4/5 versus mRNA-1273 BA.1 bivalent vaccination in patients with end-stage kidney disease. Nat Commun. 2023 Sep 27;14(1):6041. doi: 10.1038/s41467-023-41678-9. PMID: 37758707.

Articles by external researchers utilizing Cancer Care Ontario data

Gupta S, Li Q, Kassam A, Rapoport A, Widger K, Chalifour K, Baxter NN, Nathan PC, Coburn NG, Sutradhar R. Specialty Palliative Care and Symptom Severity and Control in Adolescents and Young Adults With Cancer. JAMA Netw Open. 2023 Oct 2;6(10):e2338699. doi: 10.1001/jamanetworkopen.2023.38699. PMID: 37862015.

Hansford RL, Ouellette-Kuntz H, Griffiths R, Hallet J, Decker K, Dawe DE, Kristjanson M, Cobigo V, Shooshtari S, Stirling M, Kelly C, Brownell M, Turner D, Mahar A. Breast (female), colorectal, and lung cancer survival in people with intellectual or developmental disabilities: A population-based retrospective cohort study. Can J Public Health. 2024 Feb 5. doi: 10.17269/s41997-023-00844-8. Epub ahead of print. PMID: 38315327.

Iqbal J, Moineddin R, Fowler RA, Krzyzanowska MK, Booth CM, Downar J, Lau J, Le LW, Rodin G, Seow H, Tanuseputro P, Earle CC, Quinn KL, Hannon B, Zimmermann C. Socioeconomic Status, Palliative Care, and Death at Home Among Patients with Cancer Before and During COVID-19. JAMA Netw Open. 2024 Feb 5;7(2):e240503. doi: 10.1001/jamanetworkopen.2024.0503. PMID: 38411960.

Kim SJ, Tworoger SS, Rosen BP, McLaughlin JR, Risch HA, Narod SA, Kotsopoulos J. Impact of Pre-Diagnostic Risk Factors on Short-and Long-Term Ovarian Cancer Survival Trajectories: A Longitudinal Observational Study. Cancers. 2024 Feb 28;16(5):972.

Lubinski J, Kotsopoulos J, Moller P, Pal T, Eisen A, Peck L, Karlan BY, Aeilts A, Eng C, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Ramon Y Cajal T, Singer CF, Neuhausen SL, Zakalik D, Cybulski C, Gronwald J, Huzarski T, Stempa K, Dungan J, Cullinane C, Olopade OI, Metcalfe K, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations. JAMA Oncol. 2024 Feb 29:e236944. doi: 10.1001/jamaoncol.2023.6944. Epub ahead of print. PMID: 38421676.

Metcalfe K, Huzarski T, Gronwald J, Kotsopoulos J, Kim R, Moller P, Pal T, Aeilts A, Eisen A, Karlan B, Bordeleau L, Tung N, Olopade O, Zakalik D, Singer CF, Foulkes W, Couch F, Neuhausen SL, Eng C, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis. Br J Cancer. 2023 Nov 29. doi: 10.1038/s41416-023-02503-8. Epub ahead of print. PMID: 38030749.

O'Neill B, Yusuf A, Lofters A, Huang A, Ekeleme N, Kiran T, Greiver M, Sullivan F, Kurdyak P. Breast Cancer Screening Among Females With and Without Schizophrenia. JAMA Netw Open. 2023 Nov 1;6(11):e2345530. doi: 10.1001/jamanetworkopen.2023.45530. PMID: 38019514.

Saleem N, Nash DM, Au E, Luo B, Craig JC, Garg AX, McArthur E, Dixon SN, Teixeira-Pinto A, Lim WH, Wong G. Breast Cancer Screening, Incidence, and Mortality in Women Treated With Maintenance Dialysis: A Population-Based Cohort Study in Ontario, Canada. Kidney Int Rep. 2023 Oct 18;9(1):171-176. doi: 10.1016/j.ekir.2023.10.007. PMID: 38312783.

Seung SJ, Saherawala H, Moldaver D, Shokar S, Ammendolea C, Brezden-Masley C. Survival, treatment patterns, and costs of HER2+ metastatic breast cancer patients in Ontario between 2005 to 2020. Breast Cancer Res Treat. 2023 Dec 21. doi: 10.1007/s10549-023-07185-7. Epub ahead of print. PMID: 38127177.

Wilson BE, Booth CM, Patel S, Berry S, Kong W, Merchant SJ. First-line Palliative Chemotherapy for Colorectal Cancer: A Population-based Analysis of Delivery and Outcomes in a Single-payer Health System. Clin Oncol (R Coll Radiol). 2023 Dec 13:S0936-6555(23)00460-0. doi: 10.1016/j.clon.2023.12.003. Epub ahead of print. PMID: 38199907.