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Funded Biomarker Testing

Find an overview of funded biomarker testing in Ontario. Information listed includes diagnostic, predictive and prognostic markers, as well as a summary of testing sites.

Disponible en anglais seulement. Vous pouvez demander un version française.

Funded Biomarker Testing

4 items

BRAF testing should be performed for colorectal cancer cases with abnormal MLH1 results.

Funded Biomarker Disease Site: Colorectal

Biomarker: BRAF

Testing Method:Panel

Testing Site: Health Sciences North, Kingston Health Sciences Centre, London Health Sciences Centre, Mount Sinai Hospital, The Ottawa Hospital, Trillium Health Partners, University Health Network

Promoter Methylation testing should be performed for all MMR cases with abnormal MLH1 results*.

Funded Biomarker Disease Site: Adrenal Gland, Bladder/ Urothelial, Colorectal, Endometrium, Esophagus, Hepatobiliary, Ocular, Ovary, Pancreas, Skin, Small Bowel, Stomach

Biomarker: MLH1 Methylation

Testing Method:Methylation

Testing Site: Health Sciences North, Kingston Health Sciences Centre, London Health Sciences Centre, Mount Sinai Hospital, Trillium Health Partners, University Health Network

Reflex testing on newly diagnosed cases advanced*/metastatic colorectal or small bowel carcinoma.

Funded Biomarker Disease Site: Colorectal, Small Bowel

Biomarker: BRAF, KRAS, NRAS, PIK3CA Optional for 21/22: PTEN

Testing Method:Panel

Testing Site: Hamilton Health Sciences, Health Sciences North, Kingston Health Sciences Centre, London Health Sciences Centre, Mount Sinai Hospital, St. Joseph's Healthcare Hamilton, Sunnybrook Health Sciences Centre, The Ottawa Hospital, Trillium Health Partners, University Health Network, William Osler Health System

Reflex testing on newly diagnosed tumours with invasive colorectal cancer.

Funded Biomarker Disease Site: Colorectal

Biomarker: MLH!, MSH2, MSH6, PMS2

Testing Method:Immunohistochemistry (IHC)

Testing Site: Hamilton Health Sciences, Health Sciences North, Kingston Health Sciences Centre, London Health Sciences Centre, Markham Stouffville Hospital (Oak Valley Health), Mount Sinai Hospital, North York General Hospital, Southlake Regional Health Centre, St. Joseph's Healthcare Hamilton, Sunnybrook Health Sciences Centre, The Ottawa Hospital, Trillium Health Partners, Unity Health - St. Michael's Hospital, University Health Network, William Osler Health System